TL;DR: If you are replacing 54Gene, the closest options are Docbot, Biocogniv, Medicare Vox (fka Fair Square). The table below compares 12 alternatives on what they do, stage, size and status.
Every alternative below is compared on what it actually does, not just its category — so you can see which one genuinely replaces 54Gene (YC Winter 2019).
Last verified:
The three closest alternatives to 54Gene are:
| Alternative | What it does | Stage | Team | Status |
|---|---|---|---|---|
| Docbot | — | YC Winter 2019 | — | Acquired |
| Biocogniv | — | YC Summer 2020 | 6 | Acquired |
| Medicare Vox (fka Fair Square) | Building an AI Health Insurance Agent. | YC Winter 2020 | 20 | Active |
| Zen | Posture correction software | YC Summer 2021 | — | Active |
| Mighty Health | All-in-one health program helping seniors with their daily function | YC Summer 2019 | 7 | Inactive |
| CareOasis | Get Paid for Family Caregiving | YC Summer 2023 | 2 | Active |
| Mind Emulation Foundation | — | YC Winter 2018 | 1 | Active |
| SpringWit | Brain health and awareness | YC Summer 2014 | — | Inactive |
| Digi-Prex | Subscription pharmacy for patients with chronic diseases | YC Summer 2019 | 32 | Active |
| Stitch Health | Care Coordination Platform for Healthcare | YC Summer 2015 | 2 | Inactive |
| Healthlane | Africa's Preventative Health System | YC Winter 2020 | 15 | Active |
| Bristle | At-home oral health testing, coaching & care | YC Winter 2021 | 6 | Active |
It depends on your size. Docbot is the closest match on what 54Gene actually does. If you need something more established, sort the table by team size — larger teams generally mean more support and a longer track record. If budget is the constraint, the earlier-batch companies are usually the ones still competing on price.
54Gene is no longer listed as active, so anyone still relying on it should plan a migration to one of the alternatives above.
Every company here is Y Combinator-backed and was matched to 54Gene on what it actually does — its own description of its product — rather than on a broad category label. Batch, team size and operating status come from the YC directory and are shown as-is. We do not rank by payment.
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