Y Combinator Therapeutics Startups

64 Y Combinator-backed Therapeutics companies across 19 batches — with batch, status, and location for every startup.

Total
64
Active
53
Acquired
4
Public
0
Shut down
7

Y Combinator has backed 64 Therapeutics companies across 19 batches. Of these, 53 are still active, 4 have been acquired, 0 have gone public, and 7 have shut down. Below is every YC-backed Therapeutics startup grouped by batch, with links to each company profile.

YC Spring 2026 — 1 Therapeutics startups

  • FinalDose — Programmable DNA drug destroying all cancers, unlocking 80% of targets

YC Summer 2026 — 1 Therapeutics startups

  • WonderTx — Extrapolative AI to unlock First-in-Class drugs

YC Winter 2025 — 2 Therapeutics startups

YC Summer 2025 — 1 Therapeutics startups

  • Blank Bio — RNA intelligence for precision medicine

YC Winter 2024 — 6 Therapeutics startups

  • Granza Bio — Building programmable therapeutics for the immune system
  • ParcelBio — Elevated mRNA for transformative medicines.
  • Velorum Therapeutics — Breakthrough medicines unlocking the biology of heme
  • SynsoryBio — "If-then" conditional logic for protein drugs
  • Eris Biotech — Our drugs engage the immune system to fight tumors
  • Junction Bioscience — AI Hypothesis Engine for Molecular Discovery

YC Summer 2024 — 2 Therapeutics startups

  • Evolvere BioSciences — Making Next-Generation Antibiotics that Outpace Bacterial Evolution
  • Kopra Bio — Genetically engineered viruses that teach your immune system to kill…

YC Winter 2023 — 1 Therapeutics startups

  • Modulari-T — We teach your immune system to attack and cure cancer

YC Summer 2022 — 5 Therapeutics startups

YC Winter 2022 — 3 Therapeutics startups

  • Engage Bio — Potent, durable, and redosable non-viral genetic medicines
  • Origami Therapeutics, Inc. — Oral drugs to halt neurodegeneration
  • Alixia — Targeting the Tumor Ecosystem to address cancer drug resistance.

YC Summer 2021 — 6 Therapeutics startups

YC Winter 2021 — 6 Therapeutics startups

YC Winter 2020 — 4 Therapeutics startups

  • Altay Therapeutics — Altay develops disease-modifying therapies targeting transcription…
  • OpenBiome — A nonprofit stool bank enabling access to fecal transplants.
  • Equator Therapeutics — We are developing a drug to burn calories and increase metabolism…
  • Ochre Bio — RNA medicines for liver diseases

YC Summer 2020 — 2 Therapeutics startups

  • Kernal Biologics — Kernal is creating mRNA 2.0 therapies that work in specific cells
  • Nephrogen — Curative genetic medicines for kidney diseases

YC Winter 2019 — 7 Therapeutics startups

YC Summer 2019 — 3 Therapeutics startups

YC Winter 2018 — 5 Therapeutics startups

YC Summer 2018 — 7 Therapeutics startups

  • Dorian Therapeutics — New therapeutics to rejuvenate tissue and treat age-related diseases
  • dNovo — The cure for hair loss.
  • Hepatx — Replacing organ transplant with an infusion
  • Perception Biosystems — Democratizing gene therapy by reinventing its manufacturing and…
  • Rejuvenation Technologies Inc. — mRNA therapeutics to extend healthspan entering clinical trials
  • Circumvent — Utilizing monogenic disorders to inform and solve highly complex…
  • Gerostate Alpha — Developing novel therapeutics for aging and chronic disease

YC Summer 2017 — 1 Therapeutics startups

  • Forever Labs — We bank your stem cells to help you live healthier, longer.

YC Winter 2017 — 1 Therapeutics startups

  • Sigma Genetics — Sigma Genetics is a biotechnology company that is building…

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