Origin alternatives
TL;DR: 12 companies doing similar work to Origin in Healthcare, ranked by how closely they match what Origin actually does — not just by category.
How this list was built: every company here is Y Combinator-backed and shares at least one category with Origin. They are scored on how closely their own description overlaps with Origin's, and all facts shown come from the YC company records — nothing is estimated.
What are the best alternatives to Origin?
| Alternative | What it does | Batch | Team | Status |
|---|---|---|---|---|
| Atlas Discovery | AI-native pharma company | Summer 2026 | 3 | Active |
| Avro Life Science | Skin patches for generic drug delivery. | Winter 2018 | 8 | Active |
| Synkrino Biotherapeutics | Synkrino's AI, SATIS is a powerful, unbiased discovery system for… | Summer 2018 | 2 | Active |
| General Proximity | The next generation of induced-proximity medicines. | Winter 2020 | 15 | Active |
| Pardes Biosciences | We break viruses | Summer 2020 | 2 | Public |
| Reverie Labs | Engineering next-generation, brain-penetrant cancer therapies. | Winter 2018 | 29 | Inactive |
| Exonic | Exonic is an AI-native cell and gene therapeutics company. | Fall 2025 | 3 | Active |
| Sixfold Bioscience | Delivering RNA therapies. | Winter 2018 | 27 | Active |
| Felix Biotechnology | We’re creating programmable therapies | Winter 2020 | 6 | Inactive |
| Strand AI | Multimodal foundation models to predict uncollected patient biology | Winter 2026 | 2 | Active |
| Sequence Bio | Discovering the true signals of disease to power life-changing drugs. | Summer 2019 | 52 | Active |
| Coral Genomics | New clinical tests for managing autoimmune treatments. | Summer 2018 | 5 | Acquired |
Is Origin still active?
Origin is still operating, so switching is a choice rather than a forced migration. Compare on fit and price rather than urgency.
How was this list put together?
Every company here is Y Combinator-backed and shares at least one category with Origin. They are then ranked on how closely their own description overlaps with Origin's, so the closest matches come first rather than whoever happens to share a tag.