Thesis (YC Fall 2025)

TL;DR: Thesis is a Y Combinator Fall 2025 startup Autonomous AI research, currently active with a team of 3.

Autonomous AI research

YC ID
30928
YC Batch
Fall 2025
Status
Active
Team size
3
Industry
B2B
Tags
Hard Tech, Machine Learning, Automation
YC profile
https://www.ycombinator.com/companies/thesis

Last verified:

Thesis is an AI research lab automating AI R&D itself. We are building Darwin, a hill-climbing machine capable of searching vast combinatorial spaces of experiments. By using the outcome of every experiment to optimize the next, Darwin turns machine learning research into a compounding system rather than a sequence of manual attempts. We are directing this machine toward the grand challenges of biology and materials science. Our mission is to build the machine that discovers the next Transformer, the next AlphaFold, and the breakthroughs that push science and engineering to the absolute frontier.

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Frequently asked questions

Is Thesis a YC (Y Combinator) company?

Yes. Thesis was funded by Y Combinator in the Fall 2025 batch. Autonomous AI research

What does Thesis do?

Thesis is an AI research lab automating AI R&D itself. We are building Darwin, a hill-climbing machine capable of searching vast combinatorial spaces of experiments. By using the outcome of every experiment to optimize the next, Darwin turns machine learning research into a compounding system rather than a sequence of…

What YC batch was Thesis in?

Thesis was part of Y Combinator's Fall 2025 batch.

How big is Thesis?

Thesis has a team of 3 people according to Y Combinator's directory.

Is Thesis still active?

Thesis is currently listed as Active with a team of 3 in Y Combinator's directory.

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